DESCRIPTION
Melatonin dissolvable and scored tablets provided by Douglas Laboratories®, contain 1 mg of highest purity
melatonin produced under strict Good Manufacturing Practices (GMP) standards. The natural vanilla-flavored
tablets are sweetened exclusively with xylitol and mannitol.
FUNCTIONS
Melatonin is a natural hormone nutrient that is synthesized from the amino acid tryptophan by the pineal gland
in the back of the brain. Melatonin also occurs in small amounts in a variety of foods. In the body, melatonin
appears to regulate sleep/wake cycles, support normal immune function, and protect cells from free radical
damage. Most of the research on melatonin has focused on its role in maintaining normal sleep/wake rhythms.
The perception of daylight in the eyes is a signal for the pineal gland to inhibit melatonin synthesis and release.
At night or in the dark, the body’s melatonin production rises. The rise in plasma melatonin is thought to be
responsible for bringing on sleep. Nocturnal melatonin production is highest in children and begins to decline
from adolescence on until it is virtually absent in the elderly. Melatonin supports normal immune function by
helping maintain the activity of circulating natural killer cells. It also has been found to function as an
antagonist for stress-induced immune-suppression. Melatonin is considered a potent antioxidant that enters all
body cells to help prevent free radical damage. In the brain, melatonin is perhaps the most important
physiological antioxidant. Due to its lipid and water-soluble properties, it can freely cross the blood-brain
barrier. In vitro studies show that melatonin is more effective than glutathione in scavenging toxic hydroxyl
radicals, and also more efficient than vitamin E in neutralizing peroxyl radicals which can induce DNA damage.
Furthermore, melatonin stimulates the main antioxidant enzyme of the brain, glutathione peroxidase.
INDICATIONS
Melatonin 1 mg may be a useful nutritional adjunct for individuals who wish to supplement their diet with
melatonin and support the body’s pineal gland function.
FORMULA (#MEL-S)
Each scored tablet contains:
Melatonin........................................................................1 mg
Other ingredients: Cellulose, mannitol, xylitol, vegetable stearate, silica, and natural vanilla flavor
SUGGESTED USE
As a dietary supplement, adults take 1 tablet before bedtime or as directed by a healthcare professional. Allow
tablet to dissolve in mouth and then swallow.
Tablets are scored to allow convenient administration of half dose increments.
This product is intended for occasional sleep disturbances or jet lag; for use beyond 4 weeks consult your
healthcare professional.
Warning: Not to be taken by children, pregnant or lactating women. If you are taking MAO inhibitors,
immunosuppressant drugs, anticoagulation therapy, or antihypertensive medication, or have an autoimmune,
seizure, psychiatric or depressive disorder consult your healthcare professional before using this product. Do
not take with alcohol.
SIDE EFFECTS
Long-term use of melatonin has not been studied. May cause drowsiness. Do not use before or while
operating a motor vehicle or heavy machinery
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